Christina Wichmann

As a microbiologist by training and a PhD in chemistry, I am very interested in interdisciplinary research. My main focus is on the effect of different antibacterial molecules to lipid dynamics in bacterial membranes. To understand the mode of action I apply general microbiological as well microscopic methods like fluorescent assays, confocal and super resolution microscopy. I want to understand the changes of the membranes in a time resolved as well as a special resolved  manner on living cells. 

Selected Publication list

• Wichmann, C., Dengler, J, Hoffmann, M, Rösch, P,. Popp, J. Simulating a reference medium for determining bacterial growth in hospital wastewater for Raman spectroscopic investigation. 2024  Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. doi: 10.1016/j.saa.2023.123425 
• Ramoji, A., Pahlow, S., Pistiki, A., Rüger, J., Shaik, T., Shen, H., Wichmann, C. Krafft, C., Popp, J. . 2022. Understanding viruses and viral infections by biophotonic methods. Translational Biophotonics 4. doi: 10.1002/tbio.202100008.
• Wichmann, C., P. Rösch, J. Popp. 2021. Isolation of bacteria from artificial bronchoalveolar lavage fluid using density gradient centrifugation and their accessibility by raman spectroscopy. Anal Bioanal Chem 413:5193-5200. doi: 10.1007/s00216-021-03488-0.
• Wichmann, C., T. Bocklitz, P. Rösch, J. Popp. 2021. Bacterial phenotype dependency from co2 measured by raman spectroscopy. Spectrochim Acta A 248. doi: ARTN 11917010.1016/j.saa.2020.119170.
• Wichmann, C., M. Chhallani, T. Bocklitz, P. Rösch, J. Popp. 2019. Simulation of transportation and storage and their influence on raman spectra of bacteria. Anal Chem 91:13688-13694. doi: 10.1021/acs.analchem.9b02932.
• Neugebauer, S.,Wichmann, C., S. Bremer-Streck, S. Hagel, M. Kiehntopf. 2019. Simultaneous quantification of nine antimicrobials by LC-MS/MS for therapeutic drug monitoring in critically ill patients. Therapeutic Drug Monitoring 41:29-37. doi: 10.1097/Ftd.0000000000000570.
• Lorenz, B., Wichmann, C., S. Stöckel, P. Rösch, J. Popp. 2017. Cultivation-free Raman spectroscopic Investigations of Bacteria. Trends in Microbiology 25:413-424. doi: 10.1016/j.tim.2017.01.002.

CV

2022-              Postdoc, Institute of Applied Optics and Biophysics, AG Eggeling
2021-2022      Researcher, Friedrich-Schiller-University, Jena, Institute of Physical Chemistry, AG Popp
2016-2021      PhD student, Leibniz-Institute for Photonic Technologies e.V., Jena, Germany, AG Popp
2013-2016      Master’s degree in Microbiology, University clinics, Jena, Germany, Institute of clinical chemistry and laboratory diagnostics, AG Kiehntopf
2010-2013      Bachelor’s degree in Biology, specialization in Microbiology, Friedrich-Schiller-University, Jena, Germany