Publications

2023

192. Galiani, Silvia, Eggeling, Christian and Reglinski, Katharina. "Super-resolution microscopy and studies of peroxisomes" Biological Chemistry, vol. 404, no. 2-3, 2023, pp. 87-106. https://doi.org/10.1515/hsz-2022-0314

191. Yang, T., Valavalkar, A., Romero-Arenas, A., Dasgupta, A., Then, P., Chettri, A., Eggeling, C., Ros, A., Pischel, U., Dietzek-Ivanšić, B., Excited-State Dynamics in Borylated Arylisoquinoline Complexes in Solution and in cellulo, Chem. Eur. J. 2023, 29, e202203468.

2022

190. Ghosh, Mausumi, Denkert, Niels, Reuter, Maren, Klümper, Jessica, Reglinski, Katharina, Peschel, Rebecca, Schliebs, Wolfgang, Erdmann, Ralf and Meinecke, Michael. "Dynamics of the translocation pore of the human peroxisomal protein import machinery" Biological Chemistry, vol. 404, no. 2-3, 2023, pp. 169-178. https://doi.org/10.1515/hsz-2022-0170

189. Wallace Z, Kopycinski J, Yang H, McCully ML, Eggeling C, Chojnacki J, Dorrell L. Immune mobilising T cell receptors redirect polyclonal CD8+ T cells in chronic HIV infection to form immunological synapses. Sci Rep. 2022;12(1):18366. doi: 10.1038/s41598-022-23228-3.

188. Kühne M, Hofmann S, Lindemann H, Cseresnyés Z, Dzierza A, Schröder D, Godmann M, Koschella A, Eggeling C, Fischer D, Figge MT, Heinze T, Heinzel T. Analysis of HDACi-Coupled Nanoparticles: Opportunities and Challenges. Methods Mol Biol. 2023;2589:129-144. doi: 10.1007/978-1-0716-2788-4_9. 

187. Insausti S, Garcia-Porras M, Torralba J, Morillo I, Ramos-Caballero A, de la Arada I, Apellaniz B, Caaveiro JMM, Carravilla P, Eggeling C, Rujas E, Nieva JL. Functional Delineation of a Protein-Membrane Interaction Hotspot Site on the HIV-1 Neutralizing Antibody 10E8. Int J Mol Sci. 2022;23(18):10767. doi: 10.3390/ijms231810767

186. Galiani S, Reglinski K, Carravilla P, Barbotin A, Urbančič I, Ott J, Sehr J, Sezgin E, Schneider F, Waithe D, Hublitz P, Schliebs W, Erdmann R, Eggeling C. Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5. Biophys Rep. 2022;2(2) doi: 10.1016/j.bpr.2022.100055​

185. Portwich FL, Carstensen Y, Dasgupta A, Kupfer S, Wyrwa R, Görls H, Eggeling C, Dietzek B, Gräfe S, Wächtler M, Kretschmer R. A Highly Fluorescent Dinuclear Aluminium Complex with Near-Unity Quantum Yield. Angew Chem Int Ed Engl. 2022 doi: 10.1002/anie.202117499

2021

185. Stumpf BH, Nowakowski P, Eggeling C, Maciołek A, Smith AS. Protein induced lipid demising in homogeneous membranes. Phys Rev Research. 2021;3, L042013.

184. Kretzer C, Shkodra B, Klemm P, Jordan PM, Schröder D, Cinar G, Vollrath A, Schubert S, Nischang I, Hoeppener S, Stumpf S, Banoglu E, Gladigau F, Bilancia R, Rossi A, Eggeling C, Neugebauer U, Schubert US, Werz O. Ethoxy acetalated dextran-based nanocarriers accomplish efficient inhibition of leukotriene formation by a novel FLAP antagonist in human leukocytes and blood. Cell Mol Life Sci. 2021 doi: 10.1007/s00018-021-04039-7.

183. Kokot B, Kokot H, Umek P, van Midden KP, Pajk S, Garvas M, Eggeling C, Koklič T, Urbančič I, Štrancar J. How to control fluorescent labeling of metal oxide nanoparticles for artefact-free live cell microscopy. Nanotoxicology. 2021 6:1-22. doi: 10.1080/17435390.2021.1973607.

182. Carravilla P, Dasgupta A, Zhurgenbayeva G, Danylchuk DI, Klymchenko AS, Sezgin E, Eggeling E. Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes. Biophys Rep. 2021;1(2) doi: 10.1016/j.bpr.2021.100023

181. Rujas E, Leaman DP, Insausti S, Carravilla P, García-Porras M, Largo E, Morillo I, Sánchez-Eugenia R, Zhang L, Cui H, Iloro I, Elortza F, Julien JP, Eggeling C, Zwick MB, Caaveiro JMM, Nieva JL. Focal accumulation of aromaticity at the CDRH3 loop mitigates 4E10 polyreactivity without altering its HIV neutralization profile. iScience. 2021;24(9):102987. doi: 10.1016/j.isci.2021.102987.

180. Urbančič I, Schiffelers L, Jenkins E, Gong W, Santos AM, Schneider F, O'Brien-Ball C, Vuong MT, Ashman N, Sezgin E, Eggeling C. Aggregation and mobility of membrane proteins interplay with local lipid order in the plasma membrane of T cells. FEBS Lett. 2021;595(16):2127-2146. doi: 10.1002/1873-3468.14153.

179. Chojnacki J, Eggeling C. Super-Resolution STED Microscopy-Based Mobility Studies of the Viral Env Protein at HIV-1 Assembly Sites of Fully Infected T-Cells. Viruses. 2021;13(4):608. doi: 10.3390/v13040608.

178. Schneider F, Sych T, Eggeling C, Sezgin E. Influence of nanobody binding on fluorescence emission, mobility, and organization of GFP-tagged proteins. iScience. 2021;24(1):101891.

177. Büttner M, Lagerholm CB, Waithe D, Galiani S, Schliebs W, Erdmann R, Eggeling C, Reglinski K. Challenges of using Expansion Microscopy for super-resolved imaging of cellular organelles. Chembiochem. doi: 10.1002/cbic.202000571.

2020

176. Lühr JJ, Alex N, Amon L, et al. Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition. Front Immunol. 2020;11:590121.

175. Gutowska-Owsiak D, Podobas EI, Eggeling C, Ogg GS, Bernardino de la Serna J. Addressing Differentiation in Live Human Keratinocytes by Assessment of Membrane Packing Order. Front Cell Dev Biol. 2020;8:573230.

174. Kühne M, Lindemann H, Grune C, et al. Biocompatible sulfated valproic acid-coupled polysaccharide-based nanocarriers with HDAC inhibitory activity. J Control Release. 2020;S0168-3659(20)30577-0.

173. Reglinski K, Steinfort-Effelsberg L, Sezgin E, Klose C, Platta HW, Girzalsky W, Eggeling C, Erdmann R. Fluidity and Lipid Composition of Membranes of Peroxisomes, Mitochondria and the ER From Oleic Acid-Induced Saccharomyces cerevisiae. Front Cell Dev Biol. 2020;8:574363.

172. Waithe D, Brown JM, Reglinski K, Diez-Sevilla I, Roberts D, Eggeling C. Object detection networks and augmented reality for cellular detection in fluorescence microscopy. J Cell Biol. 2020;219(10):e201903166.

171. Rujas E, Insausti S, Leaman DP, et al. Affinity for the Interface Underpins Potency of Antibodies Operating In Membrane Environments. Cell Rep. 2020;32(7):108037.

170. Schmidt F, Thywißen A, Goldmann M, et al. Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections. Cell Rep. 2020;32(7):108017.

169. Schneider KRA, Chettri A, Cole H, et al. Intracellular Photophysics of an Osmium Complex bearing an Oligothiophene Extended Ligand. Chemistry. 2020;10.1002/chem.202002667.

168. Sieben C, Sezgin E, Eggeling C, Manley S. Influenza A viruses use multivalent sialic acid clusters for cell binding and receptor activation. PLoS Pathog, 2020;16(7):e1008656.

167. Barbotin A, Urbančič I, Galiani S, Eggeling C, Booth M. Background Reduction in STED-FCS Using a Bivortex Phase Mask. ACS Photonics. 2020;7(7):1742-1753.

166. Tröger J, Hoischen C, Perner B, et al. Comparison of Multiscale Imaging Methods for Brain Research. Cells. 2020;9(6):1377.

165. Torralba J, de la Arada I, Carravilla P, et al. Cholesterol Constrains the Antigenic Configuration of the Membrane-Proximal Neutralizing HIV-1 Epitope. ACS Infect Dis. 2020;6(8):2155-2168.

164. Barbotin A, Urbancic I, Galiani S, Eggeling C, Booth M, Sezgin E. z-STED imaging and spectroscopy to investigate nanoscale membrane structure and dynamics. Biophys J, 2020;118(10):2448-2457.

163. Carravilla P, Nieva JL & Eggeling C. Fluorescence Microscopy of the HIV-1 Envelope. Viruses 12 (3), 348 (2020).

162. Sezgin E, Carugo D, Levental I, Stride E, Eggeling C. Creating Supported Plasma Membrane Bilayers Using Acoustic Pressure. Membranes, 10(2):30 (2020).

161. Stanly TA, Fritzsche M, Banerji S, Shrestha D, Schneider F, Eggeling C, Jackson DG. The cortical actin network regulates avidity-dependent binding of hyaluronan by the Lymphatic Vessel Endothelial receptor LYVE-1. J Biol Chem, 295(15) (2020)

160. Schneider F, Hernandez-Varas P, Lagerholm BC, Shrestha D, Sezgin E, Roberti MJ, Osatto G, Hecht F, Eggeling C, Urbančič I. High photon count rates improve the quiality of super-resolution fluorescence fluctuation spectroscopy. Journal of Physics D (2020).

2019

159. Azbazdar Y, Ozalp O, Sezgin E, Veerapathiran S, Duncan AL, Sansom MSP, Eggeling C, Wohland T, Karaca E, Ozhan G. More Favorable Palmitic Acid Over Palmitoleic Acid Modification of Wnt3 Ensures Its Localization and Activity in Plasma Membrane Domains. Front Cell Dev Biol, 7:281 (2019).

158. Bedard M, Shrestha D, Priestman DA, Wang Y, Schneider F, Matute JD, Iyer SS, Gileadi U, Prota G, Kandasamy M, Veerapen N, Besra G, Fritzsche M, Zeissig S, Shevchenko A, Christianson JC, Platt FM, Eggeling C, Blumberg RS, Salio M, Cerundolo V. Sterile activation of invariant natural killer T cells by ER-stressed antigen-presenting cells. Proc Natl Acad Sci U S A, 116(47) (2019).

157. Favard C, Chojnacki J, Merida P, Yandrapalli N, Mak J, Eggeling C, Muriaux D. HIV-1 Gag specifically restricts PI(4,5)P2 and cholesterol mobility in living cells creating a nanodomain platform for virus assembly. Science Advances, 5, eaaw8651 (2019).

156. Steinkuhler J, Sezgin E, Urbancic I, Eggeling C, Dimova R. 2019. Mechanical properties of plasma membrane vesicles correlate with lipid order, viscosity and cell density. Communications Biology, 2,337 (2019).

155. Pinkwart K, Schneider F, Lukoseviciute M, Sauka-Spengler T, Lyman E, Eggeling C, Sezgin E. Nanoscale dynamics of cholesterol in the cell membrane. Journal of Biological Chemistry, (2019)​​​​​

154. Barbotin A, Galiani S, Urbančič I, Eggeling C, Booth MJ. Adaptive optics allows STED-FCS measurements in the cytoplasm of living cells. Opt Express. 2019;27(16):23378-23395.

153. Colin-York H, Javanmardi Y, Skamrahl M, Kumari S, Chang VT, Khuon S, Taylor A, Chew TL, Betzig E, Moeendarbary E, Cerundolo V, Eggeling C, Fritzsche M. Cytoskeletal Control of Antigen-Dependent T Cell Activation. Cell Reports, 26(12), 3369-3379 (2019)​​​​​

152. Colin-York H, Li D, Korobchevskaya K, Chang VT, Betzig E, Eggeling C, Fritzsche M. Cytoskeletal actin patterns shape mast cell activation. Communications Biology, 2, 93, (2019)

151. Sezgin E, Schneider F, Galiani S, Urbančič I, Waithe D, Lagerholm BC, Eggeling C. Measuring nanoscale diffusion dynamics in cellular membranes with super-resolution STED-FCS. Nature Protocols, 14(4), 1054-1083, (2019)

150. Carravilla P, Chojnacki J, Rujas E, Insausti S, Largo E, Waithe D, Apellaniz B, Sicard T, Julien JP, Eggeling C, Nieva JL. Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions. Nature Communications, 10(1), 78, (2019)

​​149. Schermelleh L, Ferrand A, Huser T, Eggeling C, Sauer M, Biehlmaier O, Drummen GPC. Super-resolution microscopy demystified. Nature Cell Biology, 21(1), 72-84, (2019)

2018

​​148. Ando T, Bhamidimarri SP, Brending N, Colin-York H, Collinson L, De Jonge N, de Pablo PJ, Debroye E, Eggeling C, Franck C, Fritzsche M, Gerritsen H, Giepmans BNG, Grunewald K, Hofkens J, Hoogenboom JP, Janssen KPF, Kaufman R, Klumpermann J, Kurniawan N, Kusch J, Liv N, Parekh V, Peckys DB, Rehfeldt F, Reutens DC, Roeffaers MBJ, Salditt T, Schaap IAT, Schwarz US, Verkade P, Vogel MW, Wagner R, Winterhalter M, Yuan H, Zifarelli G. The 2018 correlative microscopy techniques roadmap. Journal of Physics D, 51(44), 443001, (2019)

147. Felce JH, Sezgin E, Wane M, Brouwer H, Dustin ML, Eggeling C, Davis SJ. CD45 exclusion- and cross-linking-based receptor signaling together broaden FcεRI reactivity. Science Signalling, 11(561), (2018)

146. Jenkins E, Santos AM, O'Brien-Ball C, Felce JH, Wilcock MJ, Hatherley D, Dustin ML, Davis SJ, Eggeling C, Sezgin E. Reconstitution of immune cell interactions in free-standing membranes. Journal of Cell Science, 132(4), (2018)

145. Urbančič I, Brun J, Shrestha D, Waithe D, Eggeling C, Chojnacki J. Lipid Composition but Not Curvature Is the Determinant Factor for the Low Molecular Mobility Observed on the Membrane of Virus-Like Vesicles. Viruses, 10(8), (2018)

144. Lyman E, Hsieh CL, Eggeling C. From Dynamics to Membrane Organization: Experimental Breakthroughs Occasion a "Modeling Manifesto". Biophysical Journal, 115(4), 595-604, (2018)

143. Urbančič I, Garvas M, Kokot B, Majaron H, Umek P, Cassidy H, Škarabot M, Schneider F, Galiani S, Arsov Z, Koklic T, Matallanas D, Čeh M, Muševič I, Eggeling C, Štrancar J. Nanoparticles Can Wrap Epithelial Cell Membranes and Relocate Them Across the Epithelial Cell Layer. Nano Letters, 18(8), 5294-5305, (2018)

142. Mobarak E, Javanainen M, Kulig W, Honigmann A, Sezgin E, Aho N, Eggeling C, Rog T, Vattulainen I. How to minimize dye-induced perturbations while studying biomembrane structure and dynamics: PEG linkers as a rational alternative. BBA Biomembranes, 1860(11), 2436-2445, (2018)

141. Schneider F, Waithe D, Lagerholm BC, Shrestha D, Sezgin E, Eggeling C, Fritzsche M. Statistical Analysis of Scanning Fluorescence Correlation Spectroscopy Data Differentiates Free from Hindered Diffusion. ACS Nano, 12(8), 8540-8546, (2018)

140. Basu S, Needham LM, Lando D, Taylor EJR, Wohlfahrt KJ, Shah D, Boucher W, Tan YL, Bates LE, Tkachenko O, Cramard J, Lagerholm BC, Eggeling C, Hendrich B, Klenerman D, Lee SF, Laue ED. FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells. Nature Communications, 9(1), 2520, (2018)

139. Schneider F, Waithe D, Galiani S, Bernardino de la Serna J, Sezgin E, Eggeling C. Nanoscale Spatiotemporal Diffusion Modes Measured by Simultaneous Confocal and Stimulated Emission Depletion Nanoscopy Imaging. Nano Letters, (2018)

​138. Chojnacki J, Eggeling C. Super-resolution fluorescence microscopy studies of human immunodeficiency virus. Retrovirology, (2018)

137. Reina F, Galiani S, Shrestha D, Sezgin E, de Wit G, Cole D, Christoffer Lagerholm B, Kukura P, Eggeling C. Complementary studies of lipid membrane dynamics using iSCAT and super-resolved fluorescence correlation spectroscopy. Journal of Physics D, (2018)

136. Xiong Y, Jentzsch AV, Osterrieth JWM, ​Sezgin E, Sazanovich IV, Reglinski K, Galiani S, Parker AW, Eggeling C and
Anderson HL. Spironaphthoxazine switchable dyes for biological imaging Chemical Science, (2018)

135. Hertzog J, Dias Junior AG, Rigby RE, Donald CL, Mayer A, Sezgin E, Song C, Jin B, Hublitz P, Eggeling C, Kohl A, Rehwinkel J. Infection with a Brazilian isolate of Zika virus generates RIG-I stimulatory RNA and the viral NS5 protein blocks type I IFN induction and signaling. European Journal of Immunology, (2018)

134. Gutowska-Owsiak D, de La Serna JB, Fritzsche M, Naeem A, Podobas EI, Leeming M, Colin-York H, O'Shaughnessy R, Eggeling C, Ogg GS. Orchestrated control of filaggrin-actin scaffolds underpins cornification. Cell Death Dis, 9(4), 412, (2018)

133. Santos AM, Ponjavic A, Fritzsche M, Fernandes RA, de la Serna JB, Wilcock MJ, Schneider F, Urbančič I, McColl J, Anzilotti C, Ganzinger KA, Aßmann M, Depoil D, Cornall RJ, Dustin ML, Klenerman D, Davis SJ, Eggeling C, Lee SF. Capturing resting T cells: the perils of PLL. Nature Immunology, 19(3), 203-205, (2018)


2017

132. Plochberger B, Röhrl C, Preiner J, Rankl C, Brameshuber M, Madl J, Bittman R, Ros R, Sezgin E, Eggeling C, Hinterdorfer P, Stangl H, Schütz GJ. HDL particles incorporate into lipid bilayers - a combined AFM and single molecule fluorescence microscopy study. Scientific Reports, 7(1), 15886, (2017)

131. Waithe D, Schneider F, Chojnacki J, Clausen MP, Shrestha D, de la Serna JB, Eggeling C. Optimized processing and analysis of conventional confocal microscopy generated scanning FCS data. Methods, (2017)

130. Chojnacki J, Waithe D, Carravilla P, Huarte N, Galiani S, Enderlein J, Eggeling C. Envelope glycoprotein mobility on HIV-1 particles depends on the virus maturation state. Nature Communications, 8(1), 545, (2017)

129. Sezgin E, Schneider F, Zilles V, Urbančič I, Garcia E, Waithe D, Klymchenko AS, Eggeling C. Polarity-Sensitive Probes for Superresolution Stimulated Emission Depletion Microscopy. Biophysical Journal, (2017)

​128. Fritzsche M, Fernandes RA, Chang VT, Colin-York H, Clausen MP, Felce JH, Galiani S, Erlenkämper C, Santos AM, Heddleston JM, Pedroza-Pacheco I, Waithe D, de la Serna JB, Lagerholm BC, Liu TL, Chew TL, Betzig E, Davis SJ, Eggeling C. Cytoskeletal actin dynamics shape a ramifying actin network underpinning immunological synapse formation. Science Advances, 3(6), e1603032, (2017)

127. Diepold A, Sezgin E, Huseyin M, Mortimer T, Eggeling C, Armitage JP. A dynamic and adaptive network of cytosolic interactions governs protein export by the T3SS injectisome. Nature Communications, 8, 15940, (2017)

126. Sezgin E, Azbazdar Y, Ng XW, Teh C, Simons K, Weidinger G, Wohland T, Eggeling C, Ozhan G. Binding of canonical Wnt ligands to their receptor complexes occurs in ordered plasma membrane environments. FEBS Journal, (2017)

​125. Sezgin E. Super-resolution optical microscopy for studying membrane structure and dynamics. Journal of Physics Condensed Matter, 29(27), 273001, (2017)

124. Aron M, Browning R, Carugo D, Sezgin E, Bernardino de la Serna J, Eggeling C, Stride E. Spectral imaging toolbox: segmentation, hyperstack reconstruction, and batch processing of spectral images for the determination of cell and model membrane lipid order. BMC Bioinformatics, 18 (1), 254 (2017)

​123. Eggeling C, Davis SJ. Macrophages: micromanagers of antagonistic signaling nanoclusters. Journal of Cell Biology, 216 (4), 871-873 (2017)

​122. Rissanen S, Grzybek M, Orlowski A, Rog T, Cramariuc O, Levental I, Eggeling C, Sezgin E, Vattulainen I. Phase Partitioning of GM1 and Its Bodipy-Labeled Analog Determine Their Different Binding to Cholera Toxin​ Frontiers in Physiology, 8, 252, (2017)

121. Schneider F, Waithe D, Clausen MP, Galiani S, Koller T, Ozhan G, Eggeling C, Sezgin E. Diffusion of lipids and GPI-anchored proteins in actin-free plasma membrane vesicles measured by STED-FCS. Molecular Biology of the Cell, 28(11), 1507-1518, (2017)

120. Sezgin E, Levental I, Mayor S, Eggeling C. The mystery of membrane organization: composition, regulation and roles of lipid rafts Nature Reviews Molecular Cell Biology, 18(6), 361-374, (2017)

119. Lagerholm CB, Andrade DM, Clausen MP, Eggeling C. Convergence of lateral dynamic measurements in the plasma membrane of live cells from single particle tracking and STED-FCS. Journal of Physics D: Applied Physics, 50 (6), 064002, (2017)

118. Pereno V, Carugo D, Bau L, Sezgin E, de la Serna JB, Eggeling E, Stride E. Electroformation of giant unilamellar vesicles on stainless steel electrodes, ACS Omega, 2(3), 994–1002 (2017)

117. Koller T, Blok S, Santos AM, Oszmiana A, Davis DM, Sezgin E, Eggeling C. Rituximab capping triggers intracellular reorganization of B cells. Matters, (2017)

116. Clausen MP, Colin-York H, Schneider F, Eggeling C, and Fritzsche M. Dissecting the actin cortex density and membrane-cortex distance in living cells by super-resolution microscopy. Journal of Physics D: Applied Physics, 50, 064002, (2017)

115. Amaro M, Reina F, Hof M, Eggeling C, Sezgin E. Laurdan and Di-4-ANEPPDHQ probe different properties of the membrane. Journal of Physics D: Applied Physics, 50(13), 134004, (2017)

114. Fritzsche M, Li D, Colin-York H, Chang VT, Moeendarbary E, Felce JH, Sezgin E, Charras G, Betzig B, Eggeling C. Self-organizing actin patterns shape membrane architecture but not cell mechanics. Nature Communications, 8, 14347 (2017)

113. Polley A, Orłowski A, Danne R, Gurtovenko AA, Bernardino de la Serna J, Eggeling C, Davis SJ, Róg T, Vattulainen I. Glycosylation and Lipids Working in Concert Direct CD2 Ectodomain Orientation and Presentation. Journal of Phys Chem Letters, 1060-1066 (2017)

​​112. Russell RA, Chojnacki J, Jones DM, Johnson E, Do T, Eggeling C, Padilla-Parra S, Sattentau QJ. Astrocytes Resist HIV-1 Fusion but Engulf Infected Macrophage Material. Cell Reports, 18(6), 1473-1483 (2017)

111. Carugo D, Aron M, Sezgin E, Bernardino de la Serna J, Kuimova MK, Eggeling C, Stride E. Modulation of the molecular arrangement in artificial and biological membranes by phospholipid-shelled microbubbles. Biomaterials, 113, 105-117 (2017)

2016

​​110. Bernardino de la Serna J, Schütz GJ, Eggeling C, Cebecauer M. There Is No Simple Model of the Plasma Membrane Organization. Frontiers in Cell and Developmental Biology, (2016)

109. Stanly TA, Fritzsche M, Banerji S, García E, Bernardino de la Serna J, Jackson DG, Eggeling C. Critical importance of appropriate fixation conditions for faithful imaging of receptor microclusters. Biology Open, 5(9), 1343-1350 (2016)

108. Xiong Y, Rivera-Fuentes P, Sezgin E, Vargas Jentzsch A, Eggeling C, Anderson HL. Photoswitchable Spiropyran Dyads for Biological Imaging. Organic Letters, 18(15), 3666-3669 (2016)

107. Galiani S, Waithe D, Reglinski K, Cruz-Zaragoza LD, Garcia E, Clausen MP, Schliebs W, Erdmann R, Eggeling C. Super resolution microscopy reveals compartmentalization of peroxisomal membrane proteins. Journal of Biological Chemistry, (2016)

106. Steshenko O, Andrade DM, Honigmann A, Mueller V, Schneider F, Sezgin E, Hell SW, Simons M, Eggeling C. Reorganization of Lipid Diffusion by Myelin Basic Protein as Revealed by STED Nanoscopy. Biophysical Journal, 110(11), 2441-2450 (2016)

105. Hölttä-Vuori M, Sezgin E, Eggeling C, Ikonen E. Use of BODIPY-cholesterol (TF-Chol) for visualizing lysosomal cholesterol accumulation. Traffic, (2016)

104. Eggeling C, Honigmann A. Closing the gap: The approach of optical and computational microscopy to uncover biomembrane organization. BBA-Biomembranes, (2016)

103. Colin-York H, Shrestha D, Felce JH, Waithe D, Moeendarbary E, Davis SJ, Eggeling C, Fritzsche M. Super-Resolved Traction Force Microscopy (STFM). Nano Letters, 16(4), 2633-2638 (2016)

102. Sezgin E, Eggeling C. Chasing Lipid Rafts. Pan European Networks: Science & Technology, 18, 162-163, (2016)

101. van der Velde JH, Oelerich J, Huang J, Smit JH, Aminian Jazi A, Galiani S, Kolmakov K, Guoridis G, Eggeling C, Herrmann A, Roelfes G, Cordes T. A simple and versatile design concept for fluorophore derivatives with intramolecular photostabilization. Nature Communications, 7, 10144 (2016)

100. Sezgin E, Can FB, Schneider F, Clausen MP, Galiani S, Stanly TA, Waithe D, Colaco A, Honigmann A, Wuestner D, Platt F, Eggeling C. A comparative study on fluorescent cholesterol analogs as versatile cellular reporters. Journal of Lipid Research, 57(2), 299-309 (2016)

2015

99. M. Fritzsche and C. Eggeling. Potential of Super Resolution, Pan-European Networks: Science & Technology, 17, (2015)

98. Neuhaus A, Eggeling C, Erdmann R, Schliebs W. Why do peroxisomes associate with the cytoskeleton? . BBA - Molecular Cell Research (2015)

97. Waithe D, Clausen MP, Sezgin E, Eggeling C. FoCuS-point: Software for STED Fluorescence Correlation and Time-Gated Single Photon Counting. Bioinformatics (2015)

96. Fritzsche M, Fernandes RA, Colin-York H, Santos AM, Lee SF, Lagerholm BC, Davis SJ, Eggeling C. CalQuo: automated, simultaneous single-cell and population-level quantification of global intracellular Ca(2+) responses. Scientific Reports, 5, 16487 (2015)

95. Reglinski K, Keil M, Altendorf S, Waithe D, Eggeling C, Schliebs W, Erdmann R. Peroxisomal Import Reduces the Proapoptotic Activity of Deubiquitinating Enzyme USP2. PLoS One. 10(10):e0140685 (2015)

94. ​Platta HW, Brinkmeier R, Reidick C, Galiani S, Clausen MP, Eggeling C. Regulation of peroxisomal matrix protein import by ubiquitination.
Biochim Biophys Acta. (2015)

93. Vicidomini G, Ta H, Honigmann A, Mueller V, Clausen MP, Waithe D, Galiani S, Sezgin E, Diaspro A, Hell SW, Eggeling C. STED-FLCS: An Advanced Tool to Reveal Spatiotemporal Heterogeneity of Molecular Membrane Dynamics. Nano Letters, 15(9):5912-5918 (2015)

92. Clausen MP, Sezgin E, de la Serna JB, Waithe D, Christoffer Lagerholm B, Eggeling C. A straightforward approach for gated STED-FCS to investigate lipid membrane dynamics. Methods, 88:67-75 (2015)

91. Andrade DM, Clausen MP, Keller J, Mueller V, Wu C, Bear JE, Hell SW, Lagerholm BC, Eggeling C. Cortical actin networks induce spatio-temporal confinement of phospholipids in the plasma membrane - a minimally invasive investigation by STED-FCS. Scientific Reports, 5, 11454-11466 (2015)

91. Eggeling C, Willig KI, Sahl SJ, Hell SW. Lens-based fluorescence nanoscopy. Q Rev Biophys, 48(2), 178-243 (2015)

90. Sezgin E, Davis SJ, Eggeling C. Membrane Nanoclusters—Tails of the Unexpected. Cell, 161, 433-434 (2015)

89. Sezgin E, Waithe D, Bernardino de la Serna J, Eggeling C. Spectral Imaging to measure heterogeneity in membrane lipid packing. Chemphyschem, 16(7):1387-94 (2015)

88. C. Eggeling. Super-resolution optical microscopy of lipid plasma membrane dynamics. Essays in Biochemistry, 57:69-80 (2015)

87. D. Milovanovic, A. Honigmann, S. Koike, F. Göttfert, P. Pähler, M. Junius, S. Müllar, U. Diederichsen, A. Janshoff, H. Grubmüller, H.J. Risselada, C. Eggeling, S.W. Hell, G. van den Bogaart, R. Jahn. Hydrophobic mismatch sorts SNARE proteins into distinct membrane domains. Nature Communications, 6:5984 (2015)


2014

86. A. Honigmann, V. Mueller, H. Ta, A. Schoenle, E. Sezgin, S.W. Hell, C. Eggeling. Scanning STED-FCS reveals spatiotemporal heterogeneity of lipid interaction in the plasma membrane of living cells. Nature Communications, 5:5412 (2014)

85. K.M. Spillane, J. Ortega-Arroyo, G. de Wit, C. Eggeling, H. Ewers, M.I. Wallace, P. Kukura. High-Speed Single-Particle Tracking of GM1 in Model Membranes Reveals Anomalous Diffusion due to Interleaflet Coupling and Molecular Pinning. Nano Letters 10;14(9):5390-7 (2014)

84. S.K. Saka, A. Honigmann, C. Eggeling, S.W. Hell, T. Lang, S.O. Rizzoli. Multi-protein assemblies underlie the mesoscale organization of the plasma membrane. Nature Communications 5:4509 (2014)

83. C. Eggeling, M. Heilemann. Editorial overview: Molecular imaging. Curr Opin Chem Biol. (2014)

82. A. Schönle, C. Von Middendorff, C. Ringemann, S.W. Hell, C. Eggeling. Monitoring triplet state dynamics with fluorescence correlation spectroscopy: bias and correction. Microsc Res Tech. 77(7):528-36 (2014)

81. A. Honigmann, S. Sadeghi, J. Keller, S. W. Hell, C. Eggeling, R. Vink. A lipid bound actin meshwork organizes liquid phase separation in model membranes, eLife e01671 (2014)

80. C. Guzmán, M. Šolman, A. Ligabue, O. Blaževitš, D. M. Andrade, L. Reymond, C. Eggeling, D. Abankwa. The efficacy of Raf kinase recruitment to the GTPase H-ras depends on H-ras membrane conformer specific nanoclustering, JBC doi: 10.1074/jbc.M113.537001 (2014)

79. S. J. Sahl, M. Leutenegger, S. W. Hell, C. Eggeling. High-Resolution Tracking of Single-Molecule Diffusion in Membranes by Confocalized and Spatially Differentiated Fluorescence Photon Stream Recording, ChemPhysChem 15, 771-783 (2014)


2013

78. M. P. Clausen, S. Galiani, J. Bernardino de la Serna, M. Fritzsche, J. Chojnacki, K. Gehmlich, B. C. Lagerholm, C. Eggeling* Pathways to optical STED microscopy, NanoBioImaging 1, 1-12 (2013)

77. M. Solanko, A. Honigmann, H. S. Midtiby, F. W. Lund, J. Brewer, V. Dekaris, R. Bittman, C. Eggeling, D. Wüstner, Membrane orientation and lateral diffusion of BODIPY-cholesterol as a function of probe structure, Biophys J 105, 2082-2092 (2013)

76. A. Chmyrov, J. Keller, T. Grotjohann, M. Ratz, E. d'Este, S. Jakobs, C. Eggeling, S. W. Hell, Nanoscopy with more than 100,000 ‘doughnuts’, Nature Methods 10, 737–740 (2013)

75. A. Honigmann, G. van den Bogaart, E. Iraheta, H. J. Risselada, D. Milovanovic, V. Mueller, S. Müllar, U. Diederichsen, D. Fasshauer, H. Grubmüller, S. W. Hell, C. Eggeling, K. Kühnel, R. Jahn, Phosphatidylinositol 4,5-bisphosphate clusters act as molecular beacons for vesicle recruitment, Nature Structural Molecular Biology 20, 679-686 (2013)

74. G. Vicidomini, A. Schönle, H. Ta, K. Y. Han, G. Moneron, C. Eggeling, S. W. Hell STED Nanoscopy with Time-Gated Detection: Theoretical and Experimental Aspects, PLOS One 8, e54421 (2013)

73. G. Lukinavičius, K. Umezawa, N. Olivier, A. Honigmann, G. Yang, T. Plas, V. Mueller, L. Reymond, I. R. Corrêa Jr, Z.-G. Luo, C. Schultz, E. A. Lemke, P. Heppenstall, C. Eggeling, S. Manley, K. Johnsson A near-infrared fluorophore for live-cell superresolution microscopy of cellular proteins, Nature Chemistry 5, 132-139 (2013)

72. A. Honigmann, V. Mueller, S. W. Hell, C. Eggeling* STED microscopy detects and quantifies liquid phase separation in lipid membranes using a new far-red emitting fluorescent phosphoglycerolipid analogue, Faraday Discussion 161, 77–89 (2013)


2012

71. T. Grotjohann, I. Testa, M. Reuss, T. Brakemann, C. Eggeling, S. W. Hell, S. Jakobs rsEGFP2 enables fast RESOLFT nanoscopy of living cells, eLife 1:e00248 (2012)

70. K. Y. Han, D. Wildanger, E. Rittweger, J. Meijer, S. Pezzagna, S. W. Hell, C. Eggeling* Dark state photophysics of diamond nitrogen-vacancy centres, New J Physics 14, 123002 (2012)

69. M. Bally, G. E. Rydell, R. Zahn, W. Nasir, C. Eggeling, M. E. Breimer, L. Svensson, F. Hook, G. Larson Norovirus GII.4 Virus-like Particles Recognize Galactosylceramides in Domains of Planar Supported Lipid Bilayers, Angewandte Chemie Int Edition 51, 12020 –12024 (2012)

68. I. Testa, N. T. Urban, S. Jakobs, C. Eggeling, K. I. Willig, S. W. Hell Nanoscopy of Living Brain Slices with Low Light Levels, Neuron 75, 992 – 1000 (2012).

67. E. Szegin, I. Levental, M. Grzybek, G. Schwarzmann, V. Mueller, A. Honigmann, V.N. Belov, C. Eggeling, Ü. Coskun, K. Simons, P. Schwille Partitioning, diffusion, and ligand binding of raft lipid analogs in model and cellular plasma membranes, BBA Biomembranes 1818, 1777–1784 (2012).

66. M. Leutenegger, C. Ringemann, T. Lasser, S.W. Hell, C. Eggeling* Fluorescence correlation spectroscopy with a total internal reflection fluorescence STED microscope (TIRF-STED-FCS), Opt. Expr. 20, 5243 – 5263 (2012).

65. G. Vicidomini, G. Moneron, C. Eggeling, E. Rittweger, S.W. Hell, STED with wavelengths closer to the emission maximum, Opt. Expr. 20, 5225 – 5236 (2012).


2011

64. V. Mueller, C. Ringemann, A. Honigmann, G. Schwarzmann, R. Medda, M. Leutenegger, S. Polyakova, V.N. Belov, S.W. Hell, C. Eggeling* STED Nanoscopy Reveals Molecular Details of Cholesterol- and Cytoskeleton-Modulated Lipid Interactions in Living Cells, Biophys. J. 101, 1651 – 1660 (2011).

63. T. Grotjohann, I. Testa, M. Leutenegger, H. Bock, N. T. Urban, F. Lavoie-Cardinal, K.I. Willig, C. Eggeling, S. Jakobs, S.W. Hell Diffraction-unlimited all-optical imaging and writing with a photochromic GFP, Nature 478, 204 – 208 (2011).

62. T. Brakemann, A.C. Stiel, G. Weber, M. Andresen, I. Testa, T. Grotjohann, M. Leutenegger, U. Plessmann, H. Urlaub, C. Eggeling, M. C. Wahl, S.W. Hell, S. Jakobs A reversibly photoswitchable GFP-like protein with fluorescence excitation decoupled from switching, Nature Biotechnology 29, 942 – 947 (2011).

61. G. Vicidomini, G. Moneron, K.Y. Han, V. Westphal, H. Ta, M. Reuss, J. Engelhardt, C. Eggeling, S.W. Hell Sharper low-power STED nanoscopy by time gating, Nature Methods 8, 571 – 573 (2011).


2010

60. M. Leutenegger, C. Eggeling, S.W. Hell (2010) Analytical description of STED microscopy performance, Opt. Expr. 18, 26417 – 26429 (2010).

59. J. Bierwagen, I. Testa, J. Fölling, D. Wenzel, S. Jakobs, C. Eggeling, S.W. Hell Far-Field Autofluorescence Nanoscopy, Nano Lett. 10, 4249 – 4252 (2010).

58. I. Testa, C.A. Wurm, R. Medda, E. Rothermel, C. von Middendorf , J. Fölling, S. Jakobs, A. Schönle, S.W. Hell, C. Eggeling* Multicolor fluorescence nanoscopy in fixed and living cells by exciting conventional fluorophores with a single wavelength, Biophys. J. 99, 2686 - 2694 (2010).

57. A. Honigmann, C. Walter, F. Erdmann, C. Eggeling, R. Wagner Characterization of Horizontal Lipid Bilayers as a Model System to Study Lipid Phase Separation, Biophys. J. 98, 2886 – 2894 (2010).

56. K. Kolmakov, V.N. Belov, C. A. Wurm, B. Harke, M. Leutenegger, C. Eggeling, S.W. Hell A Versatile Route to Red-Emitting Carbopyronine Dyes for Optical Microscopy and Nanoscopy, Eur. J. Org. Chem. 2010, 3593 – 3610 (2010).

55. K.Y. Han, S.K. Kim, C. Eggeling*, S. W. Hell Metastable Dark States Enable Ground State Depletion Microscopy of Nitrogen Vacancy Centers in Diamond with Diffraction-Unlimited Resolution, Nano Lett. 10, 3199 – 3203 (2010).

54. S. J. Sahl, M. Leutenegger, M. Hilbert, S. W. Hell, C. Eggeling* Fast molecular tracking maps nanoscale dynamics of plasma membrane lipids, Proc. Natl. Acad. Soc. USA 107, 6829 – 6834 (2010).

53. T. Brakemann, G. Weber, M. Andresen, G. Groenhof, A.C. Stiel, S. Trowitzsch, C. Eggeling, H. Grubmüller, S.W. Hell, M.C. Wahl, S. Jakobs Molecular basis of the light-driven switching of the photochromic fluorescent protein Padron, J. Biol. Chem. 285, 14603 – 14609 (2010).

52. G. Y. Mitronova, V.N. Belov, M.L. Bossi, C.A. Wurm, L. Meyer, R. Medda, G. Moneron, S. Bretschneider, C. Eggeling*, S. Jakobs, S.W. Hell New Fluorinated Rhodamines for Optical Microscopy and Nanoscopy, Chem Eur. J. 16, 4477 – 4488 (2010).

51. K. Kolmakov, V.N. Belov, J. Bierwagen, C. Ringemann, V. Müller, C. Eggeling, S.W. Hell Red-Emitting Rhodamine Dyes for Fluorescence Microscopy and Nanoscopy, Chemistry – A Eur. J. 16, 158 – 166 (2010).


2009

50. C. Ringemann, B. Harke, C. von Middendorff, R. Medda, A. Honigmann, R. Wagner, M. Leutenegger, A. Schönle, S.W. Hell, C. Eggeling* Exploring single-molecule dynamics with fluorescence nanoscopy, New J. Physics 11, 103054 (2009).

49. S.M. Polyakova, V.N. Belov, S.F. Yan, C. Eggeling, C. Ringemann, G. Schwarzmann, A. de Meijere, S.W. Hell New GM1 Ganglioside Derivatives for Selective Single and Double Labelling, Eur. JOC 30, 5162 – 5177 (2009).

48. K.Y. Han, K. I. Willig, E. Rittweger, F. Jelezko, C. Eggeling*, S. W. Hell Three-Dimensional Stimulated Emission Depletion Microscopy of Nitrogen-Vacancy Centers in Diamond Using Continuous-Wave Light, Nano Lett. 9, 3323 – 3329 (2009).

47. G. Donnert, C. Eggeling*, S. W. Hell Triplet-relaxation microscopy with bunched pulsed excitation, Photochem. Photobiol. Sci. 8, 481-485 (2009).

46. E. Rittweger, K. Y. Han, S. E. Irvine, C. Eggeling, S. W. Hell Stimulated emission depletion microscopy reveals crystal colour centres with nanometric resolution. Nature Photonics 3, 144-147 (2009).

45. C. Eggeling*, C. Ringemann, R. Medda, G. Schwarzmann, K. Sandhoff, S. Polyakova. V. N. Belov, B. Hein, C. von Middendorff, A. Schönle, S. W. Hell Direct observation of the nanoscale dynamics of membrane lipids in a living cell. Nature 457, 1159-1163 (2009).


2008

44. I. Testa, A. Schönle, C. von Middendorff, C. Geisler, R. Medda, C. A. Wurm, A. C. Stiel, S. Jakobs, M. Bossi, C. Eggeling, S. W. Hell, A. Egner Nanoscale separation of molecular species based on their rotational mobility. Opt. Expr. 16, 21093 – 21104 (2008).

43. J. Fölling, M. Bossi, H. Bock, R. Medda, C. A. Wurm, B. Hein, S. Jakobs, C. Eggeling*, S. W. Hell Fluorescence nanoscopy by ground-state depletion and single-molecule return. Nature Meth. 5, 943-945 (2008).

42. M. Bossi, J. Fölling, V. N. Belov, V. P. Boyarskiy, R. Medda, A. Egner, C. Eggeling, A. Schönle, S. W. Hell Multicolor Far-Field Fluorescence Nanoscopy through Isolated Detection of Distinct Molecular Species. Nano Letters 8, 2463-2468 (2008).

41. M. Andresen, A. C. Stiel, J. Fölling, D. Wenzel, A. Schönle, A. Egner, C. Eggeling, S. W. Hell, S. Jakobs, Photoswitchable fluorescent proteins enable monochromatic multilabel imaging and dual color fluorescence nanoscopy. Nature Biotechnol. 26, 1035-1040 (2008).

40. A. C. Stiel, M. Andresen, H. Bock, M. Hilbert, J. Schilde, A. Schönle, C. Eggeling, A. Egner, S. W. Hell, S. Jakobs, Generation of monomeric reversibly switchable red fluorescent proteins for far-field fluorescence nanoscopy. Biophys. J. 95, 2989-2997 (2008).

39. C. Ringemann, A. Schönle, A. Giske, C. v. Middendorff, S. W. Hell, C. Eggeling*, Enhancing Fluorescence Brightness: Effect of Reverse Intersystem Crossing Studied by Fluorescence Fluctuation Spectroscopy. ChemPhysChem 9, 612 – 624 (2008).

38. J. Fölling, V. Belov, D. Riedel, A. Schönle, A. Egner, C. Eggeling, M. Bossi, S. W. Hell, Fluorescence Nanoscopy with Optical Sectioning by Two-Photon Induced Molecular Switching using Continuous-Wave Lasers. ChemPhysChem 9, 321 – 326 (2008).


2007

37. J. J. Sieber, K. I. Willig, C. Kutzner, C. Gerding-Reimers, B. Harke, G. Donnert, B. Rammner, C. Eggeling, S. W. Hell, H. Grubmüller, T. Lang, Anatomy and dynamics of a supramolecular membrane protein cluster. Science 317, 1072-1076 (2007).

36. H. Neubauer, N. Gaiko, S. Berger, J. Schaffer, C. Eggeling, J. Tuma, L. Verdier, C. A. M. Seidel, C. Griesinger, A. Volkmer, Orientational and dynamical heterogeneity of Rhodamine 6G terminally attached to a DNA helix revealed by NMR and single-molecule fluorescence spectroscopy. J. Am. Chem. Soc. 129, 12746-12755 (2007).

35. M. Andresen, A. C. Stiel, S. Trowitzsch, G. Weber, C. Eggeling, M. C. Wahl, S. W. Hell, S. Jakobs, Structural basis for reversible photoswitching in Dronpa. Proc. Natl. Acad. Soc. USA 104, 13005-13009 (2007).

34. C. Eggeling*, M. Hilbert, H. Bock, C. Ringemann, M. Hofmann, A. C. Stiel, M. Andresen, S. Jakobs, A. Egner, A. Schönle, S. W. Hell, Reversible Photoswitching Enables Single-Molecule Fluorescence Fluctuation Spectroscopy at High Molecular Concentration. Micros. Res. Techn. 70, 1003-1009, (2007).
33. J. Fölling, V. Belov, R. Kunetsky, R. Medda, A. Schönle, A. Egner, C. Eggeling, M. Bossi, S. W. Hell, Photochromic Rhodamines Provide Nanoscopy with Optical Sectioning. Angew. Chemie Int. Ed. 46, 6266-6270 (2007).

32. A. Egner, C. Geisler, C. von Middendorff, H. Bock, D. Wenzel, R. Medda, M. Andresen, A. C. Stiel, S. Jakobs, C. Eggeling, A. Schönle, S. W. Hell, Fluorescence nanoscopy in whole cells by asynchronous localization of photoswitching emitters, Biophys. J. 93, 3285-3290 (2007).

31. H. Bock, C. Geisler, C. A. Wurm, C. von Middendorff, S. Jakobs, A. Schönle, A. Egner, S. W. Hell, C. Eggeling*, Two-color far-field fluorescence nanoscopy based on photoswitchable emitters. Appl. Phys. B 88, 161-165 (2007).

30. C. Geisler, A. Schönle, C. von Middendorff, H. Bock, C. Eggeling, A. Egner, S. W. Hell, Resolution of l/10 in fluorescence microscopy using fast single molecule photoswitching. Appl. Phys. A 88, 223-226 (2007).

29. S. Bretschneider, C. Eggeling, S. W. Hell, Breaking the Diffraction Barrier in Fluorescence Microscopy by Optical Shelving. Phys. Rev. Lett. 98, 218103 (2007).

28. G. Donnert, J. Keller, C. A. Wurm, S. O. Rizzoli, V. Westphal, A. Schönle, R. Jahn, S. Jakobs, C. Eggeling, S. W. Hell, Two-Color Far-Field Fluorescence Nanoscopy. Biophys. J. 92, L67-L69 (2007).

27. M. Schwentker, H. Bock, M. Hofmann, S. Jakobs, J. Bewersdorf, C. Eggeling*, S. W. Hell, Wide-field sub-diffraction RESOLFT microscopy using fluorescent protein photoswitching. Micros. Res. Techn. 70, 269-280 (2007).

26. A. C. Stiel, S. Trowitzsch, G. Weber, M. Andresen, C. Eggeling, S. W. Hell, S. Jakobs, M. C. Wahl, 1.8 Å bright-state structure of the reversibly switchable fluorescent protein Dronpa guides the generation of fast switching variants. Biochem. J. 402, 35-42 (2007).

25. G. Donnert, C. Eggeling, S. W. Hell, Major signal increase in fluorescence microscopy through dark-state relaxation. Nature Meth. 4, 81-86 (2007).

24. J. Widengren, A. Chmyrov, C. Eggeling, P.-A. Löfdahl, C. A. M. Seidel, Strategies to improve photostabilities in ultrasensitive fluorescence spectroscopy. J. Phys. Chem. A 111, 429-440 (2007).


2006

23. M. Leutenegger, H. Blom, J. Widengren, C. Eggeling, M. Gösch, R. A. Leitgeb, T. Lasser, Dual-color total internal reflection fluorescence cross-correlation spectroscopy. J. Biomed. Opt. 11, 040502 (2006).

22. G. Donnert, J. Keller, R. Medda, M. A. Andrei, S. O. Rizzoli, R. Lührmann, R. Jahn, C. Eggeling, S. W. Hell, Macromolecular-scale resolution in biological fluorescence microscopy. Proc. Natl. Acad. Soc. USA 103, 11440-11445 (2006).

21. C. Eggeling*, J. Widengren, L. Brand, J. Schaffer, S. Felekyan, C. A. M. Seidel, Analysis of Photobleaching in Single-Molecule Multicolor Excitation and Förster Resonance Energy Transfer Measurements. J. Phys. Chem. A 110, 2979-2995 (2006).

20. M. Hofmann, C. Eggeling, S. Jakobs, S. W. Hell, Breaking the diffraction barrier in fluorescence microscopy at low light intensities using reversibly photoswitchable proteins. Proc. Natl. Acad. Sci. USA 102, 17565-17569 (2006).


2005

19. C. Eggeling*, S. Jäger, D. Winkler, P. Kask, Comparison of Different Fluorescence Fluctuation Methods for their Use in FRET Assays: Monitoring Protease Reaction. Curr. Pharm. Biotechnol. 6, 351-371 (2005).

18. M. Andresen, M. C. Wahl, A. Stiel, F. Gräber, L. V. Schäfer, S. Trowitzsch, G. Weber, C. Eggeling, H. Grubmüller, S. W. Hell, S. Jakobs, Structure and mechanism of the reversible photoswitch of a fluorescent protein. Proc. Natl. Acad. Sci. USA 102, 13070 - 13074 (2005).

17. C. Eggeling*, P. Kask, D. Winkler, S. Jäger, Rapid Analysis of Förster Energy Transfer by Two-Color Global Fluorescence Correlation Spectroscopy: Trypsin Proteinase Reaction. Biophys. J. 89, 605-618 (2005).

16. L. Kastrup, H. Blom, C. Eggeling, S. W. Hell, Fluorescence Fluctuation Spectroscopy in Subdiffraction Focal Volumes. Phys. Rev. Lett. 94, 178104 (2005).

15. C. Eggeling*, A. Volkmer, C. A. M. Seidel, Molecular photobleaching kinetics of Rhodamine 6G under the conditions of one- and two-photon induced confocal fluorescence microscopy. ChemPhysChem 6, 791-804 (2005).


2003

14. S. Jäger, L. Brand, C. Eggeling*, New Fluorescence Techniques for High-Throughput Drug Discovery. Curr. Pharm. Biotechnol. 4, 463-476 (2003).

13. C. Eggeling, L. Brand, D. Ullmann, S. Jäger, Highly sensitive fluorescence detection technology currently available for HTS. Drug Discovery Today 8, 632-641 (2003).


2002

12. K. Palo, L. Brand, C. Eggeling, S. Jäger, P. Kask, K. Gall, Fluorescence Intensity and Lifetime Distribution Analysis: Toward Higher Accuracy in Fluorescence Fluctuation Spectroscopy. Biophys. J. 83, 605-618 (2002).


2001

11. C. Eggeling, J. Schaffer, C. A. M. Seidel, J. Korte, G. Brehm, S. Schneider, W. Schrof, Homogeneity, transport and signal properties of single Ag-particles studied by single-molecule surface enhanced resonance Raman scattering. J. Phys. Chem. A 105, 3673-3679 (2001).

10. C. Eggeling, S. Berger, L. Brand, J. R. Fries, J. Schaffer, A. Volkmer, C. A. M. Seidel, Data registration and selective single-molecule analysis using multi-parameter fluorescence detection. J. Biotechnol. 86, 163-180 (2001).


1999

9. J. Schaffer, A. Volkmer, C. Eggeling, V. Subramaniam, G. Striker, C. A. M. Seidel, Identification of single molecules in aqueous solution by time-resolved fluorescence anisotropy. J. Phys. Chem. A 103, 331-336 (1999).


1998

8. M. Börsch, P. Turina, C. Eggeling, J. R. Fries, C. A. M. Seidel, A. Labahn, P. Gräber, Conformational Changes of the H+-ATPase from E.coli upon binding detected by single molecule fluorescence. FEBS Lett. 437, 251-254 (1998).

7. J. R. Fries, L. Brand, C. Eggeling, M. Köllner, C. A. M. Seidel, Quantitative identification of different single molecules by selective time-resolved confocal fluorescence spectroscopy. J. Phys. Chem. A 102, 6601-6613 (1998).

6.** C. Eggeling, J. Widengren, R. Rigler, C. A. M. Seidel, Photobleaching of fluorescent dyes under conditions used for single-molecule detection: Evidence of two-step photolysis. Anal. Chem. 70, 2651-2659 (1998).

5. C. Eggeling, J. R. Fries, L. Brand, R. Günther, C. A. M. Seidel, Monitoring conformational dynamics of a single molecule by selective fluorescence spectroscopy. Proc. Natl. Acad. Sci. USA 95, 1556-1561 (1998).


1997

4. C. Eggeling, L. Brand, C. A. M. Seidel, Laser-induced fluorescence detection of coumarin derivatives in aqueous solution: photochemical aspects for single molecule detection. Bioimaging 5, 105-115 (1997).

3. C. A. M. Seidel, L. Brand, C. Eggeling, Single-molecule detection of Coumarin-120. Nucleosides Nucleotides 16, 551-556 (1997).

2. L. Brand, C. Eggeling, C. Zander, K. H. Drexhage, C. A. M. Seidel, Single-molecule identification of Coumarin-120 by time-resolved fluorescence detection: Comparison of one- and two-photon excitation in solution. J. Phys. Chem. A 101, 4313-4321 (1997).


1996

1. C. Zander, M. Sauer, M., K. H. Drexhage, D.-S. Ko, A. Schulz, J. Wolfrum, L. Brand, C. Eggeling, C. A. M. Seidel Detection and characterization of single molecules in aqueous solution. Appl. Phys. B 63, 517-523 (1996).