Gaukhar Zhurgenbayeva

My research interests include fluorescence microscopy and microbiology. In my doctoral research project, I’m using the gut-on-chip model to visualize and study the microbial communication with human intestine. This 3D in-vitro model closely resembles the anatomical structure of a human intestine and allows us to study the innate immune response and microbial pathogenicity mechanisms that can lead to infections, chronic inflammation and other bowel diseases.

Publication list

• Koceva, H., Amiratashani, M., Akbarimoghaddam, P., Hoffmann, B., Zhurgenbayeva, G., Gresnigt, M. S., Marcelino, V. R., Eggeling, C., Figge, M. T., Amorim, M. J., & Mosig, A. S. . Deciphering respiratory viral infections by harnessing organ-on-chip technology to explore the gut-lung axis. Open biology, 15(3), 240231, (2025).
• ​M. Valentine, P. Rudolph, A. Dietschmann, A. Tsavou, S. Mogavero, S. Lee, E. L. Priest, G. Zhurgenbayeva, N. Jablonowski, S. Timme, C. Eggeling, S. Allert, E. Dolk, J. R. Naglik, M. T. Figge, M. S. Gresnigt, B. Hube. Nanobody-mediated neutralization of candidalysin prevents epithelial damage and inflammatory responses that drive vulvovaginal candidiasis pathogenesis. mBio, e0340923 (2024).
• Carravilla P et al. Long-term STED imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes. Biophysical Reports doi: 10.1016/j.bpr.2021.100023 (2021).

CV

• Currently: Doctoral Researcher at AG Prof. Eggeling, Institute of Applied Optics and Biophysics, Fredrich-Schiller University, Jena
• 2016-2018: Master of Science in Biology. Nazarbayev University, Kazakhstan
• 2010-2014: Bachelor of Science in Biomedical Engineering. Boston University, Boston MA